IPPIC team members

Dr Julie Dodds

Julie obtained a BSc (Hons) in Sociology with Research Training at the University of Bath. She previously managed studies in primary care at UCL and the Medical Research Council. She also worked as a Senior Research Fellow at UCL for several years where she conducted sexual health research and obtained a PhD in HIV epidemiology.

Julie is the Senior Research Manager at the Women’s health Unit at Queen Mary University of London, UK. She oversees the management of all the trials and studies within the Unit. She is also a co-investigator on the IPPIC study.

 

 

Dr Richard Hooper  

Since joining the Pragmatic Clinical Trials Unit in 2010, Richard’s work has focused on the theory and practice of running clinical trials. His research interests centre on innovative approaches to clinical trial design, with the aim of improving efficiency. This work has led to publications in the British Medical Journal, the International Journal of Epidemiology, and Statistics in Medicine, among others. He has also written and distributed software (SimSam) that allows accurate and transparent sample size calculation in trial designs of any complexity, using simulation. More recently he has made important contributions in the field of stepped wedge trials (designs with a randomised delay in the introduction of an intervention at different sites) – an area that has seen an explosion of interest among statisticians, health researchers and funders.

 

 

Professor Richard Riley

Richard is a Professor of Biostatistics at Keele University, having previous held posts at the Universities of Birmingham, Liverpool and Leicester. He joined Keele in October 2014 and his role focuses on statistical and methodological research for prognosis and meta-analysis, whilst supporting clinical projects in these areas. He is also a Statistics Editor for the BMJ and a co-convenor of the Cochrane Prognosis Methods Group.

Richard co-leads a summer school in Prognosis Research Methods, and leads a number of statistical training courses for risk prediction and meta-analysis

Richard is an expert on statistical methods for meta-analysis (the combination of results across multiple studies) and prognosis research (the study of future outcomes in those with existing disease). In meta-analysis, he specialises in methods for dealing with multiple correlated outcomes, and for synthesising individual participant data (IPD). In prognosis, Richard co-leads the PROGRESS initiative (PROGnosis RESearch Strategy), that seeks to improve the standards of prognosis research. This includes statistical methods to identify prognostic factors (markers), to develop and validate prognostic models (risk prediction models), and to identify predictors of treatment response for stratified medicine (predictive markers).  He combines his meta-analysis and prognosis interests through the development and validation of prognostic models using IPD from multiple studies, and through meta-analysis of prognostic and predictive marker studies, especially in the cancer field. He has received numerous healthcare related grants, from funders including the MRC and NIHR, and has published over 100 applied and methodological research articles. He currently supervises 5 PhD students and co-supervises 3 others

 

 

Dr Kym Snell

Kym was awarded her PhD from the University of Birmingham in 2015. Her thesis explored statistical methods for prognostic research. She moved to the Research Institute for Primary Care and Health Sciences at Keele University in 2016, where she continues to work on methodology and applied research in risk prediction modelling and meta-analysis. Kym is also part of the statistical team for the IPPIC study.

 

 

 

Karel G.M. Moons is Professor of Clinical Epidemiology at the Julius Center for Health Sciences and Primary Care, UMC Utrecht, The Netherlands. He is Director of Research in the management team of the Julius Center and heading the research programme ‘Methodology’. Since 2005 he also has an Adjunct Professorship at VanderBilt University, Nashville, USA. He also is affiliated to the Cochrane Collaboration and Cochrane Netherlands. He is editor in chief of BMC Diagnostic & Prognostic Research.

Karel Moons is principal investigator in numerous international (epidemiologic and clinical) studies funded by various organisations (EU, NHS, NIH). His experience covers the full range of conduct, data analysis and reporting of such studies, varying from diagnostic test evaluation, etiologic and prognostic (bio)marker studies to therapeutic trials and meta-epidemiological studies. His main focus concerns the methodology of diagnostic and prognostic research, both primary and meta-analytical research. His major expertise is testing and introducing innovations for design and analysis for development, validation and implementation of diagnostic and prognostic biomarkers and prediction models. Clinical topics include cancer, deep vein thrombosis, heart failure and peri-operative risk assessment. He teaches graduate and postgraduate students in all aspects of epidemiologic and clinical research design, analysis and reporting, throughout the world. He has published over 425 scientific papers and book chapters and obtained numerous (methodological and applied) research grants, including large prestigious personal grants.

 

 

 

Dr Asma Khalil

Asma Khalil is a subspecialist in Maternal and Fetal Medicine and Reader at St George’s University of London. Her research interest is hypertensive disorders of pregnancy, assessment of fetal growth, multiple pregnancy and cardiovascular changes in pregnancy. Asma gained her MD at the University of London following two years’ research into pre-eclampsia. She has published more than 100 peer reviewed research papers in medical journals, focusing on screening for pre-eclampsia and fetal growth restriction. She also has a Masters degree in Epidemiology from the London School of Hygiene & Tropical Medicine and an MRC scholarship. Asma is an active member in a number of key scientific committees, such as the ISUOG Clinical Standards, the RCOG Scientific Advisory Committee and NICE Quality Standards.

 

 

 

Basky Thilaganathan was appointed Professor of Fetal Medicine at St George’s, University of London in 2008. Before that, he was appointed Director of Fetal Medicine at St George’s Hospital NHS Trust in 1999. His research interests are focused on Maternal-Fetal medicine, with a particular interest on maternal cardiac function, placental function, fetal growth and preeclampsia (TED talk: http://bit.ly/2i1SqDk). He completed his postgraduate training at King’s College London and St Bartholomew’s Hospitals, culminating in his Membership of the Royal College of Obstetricians and Gynaecologists (MRCOG) (1995) and MD in Fetal Medicine (1996). He was awarded the Fellowship of the Royal College of Obstetricians and Gynaecologists (FRCOG) and an Honorary Doctorate (PhD) from Uppsala University in 2007. He has authored two undergraduate and five postgraduate text books in obstetrics and fetal medicine. He is the lead trainer for the Maternal-Fetal medicine sub-speciality training programme at St George’s Hospital and Editor-in Chief of Ultrasound in Obstetrics and Gynaecology, the medical journal affiliated to ISUOG. He has authored over 200 peer-reviewed publications in indexed journals. He represents the Royal College of Obstetrics and Gynaecology on the UK National Screening Committee and is the Clinical Lead for the development of the first dedicated high-throughput NIPT lab in the UK NHS (www.theSAFEtest.co.uk) to undertake cfDNA aneuploidy screening in pregnancy.

 

 

 

Dr Jenny Myers

Dr Myers completed her specialist training in Obstetrics at Saint Mary's Hospital and was appointed is a Senior Lecturer/Consultant Obstetrician in 2011. She has a specialist interest in diabetes and hypertension in pregnancy and combines her clinical work with an active research programme. She leads several clinical and basic science research studies within the Maternal and Fetal Health Research Centre and runs two specialist clinical research clinic, Manchester Antenatal Vascular Service (MAViS), which cares for women with a history of high blood pressure and VELOCITY which provides specialist care for women with diabetes in pregnancy. Dr Myers was awarded the William Blair Bell Memorial Lectureship by the Royal College of Obstetricians and Gynaecologists (RCOG) in 2009. This is given to a clinician who has made an outstanding contribution to research in the field Obstetrics and Gynaecology. Her work related to pre-eclampsia has been published in many international research journals and she has contributed to several book chapters and regional clinical guidelines. Dr Myers is Secretary of Blair Bell Research Committee, has served on several NICE guideline groups and is a speciality editor for Plos Medicine.

 

 

 

  After completing a BSc degree in Statistics at University College London (2010-13), Claire completed a two-year National Institute for Health Research (NIHR) methods fellowship at the Pragmatic Clinical Trials Unit (PCTU). The fellowship involved both applied and methodological work, and as part of the fellowship Claire gained an MSc degree in Medical Statistics at the London School of Hygiene and Tropical Medicine (2013-14). Claire now works as a Statistician in the PCTU.

 

 

 

  John is a doctoral candidate at the Academic Medical Center of the University of Amsterdam. He is also the project manager on the IPPIC IPD meta-analysis. His thesis is on the prediction of complications in high-risk pregnant women. John has experience in the management of multi-centre clinical trials, and has a degree in Public Health and Health Economics from Queen Mary University of London.